Discover

Our Discovery effort is deeply collaborative and iterative. We systematically evaluate emerging fields of science and medicine that are ripe for us to bring transformative change to areas of unmet medical need. Each one of our team members has multiple decades of real-world operating experience.  Combining our experience with those of leading academics, scientific founders and expert advisors, we develop a clear vision and strategy for a company with the patient front and center.

A defining feature of our Discovery process is the extended time we take at the seed stage, validating mechanisms and maturing a lead program well before a company launches. We’ve found this pays off downstream: companies launch with more clinically credible programs and reach meaningful data faster.

Launch

New company Launch at Third Rock is designed to convert discovery maturity into clinical momentum and a high velocity path to value creation. We provide the necessary financial, technical and human resources to reach milestones critical for growth and success, become active members of the leadership team, serve in interim roles to execute the company’s R&D strategy, and build a world-class team that shares the company’s scientific vision. Importantly, we work to establish a dynamic and innovative culture at launch where the growing team has a unified passion and commitment to make a difference in the lives of patients.

Build

Once launched, Third Rock remains deeply involved in the operational execution and strategic guidance of its companies, working to ensure that the company’s development rigor, strategic focus, and long-term value creation paths are established and institutionalized.

We transition out of our interim roles and establish experienced and motivated management teams. As board members and domain experts, we work with these teams for as long as is needed to relentlessly execute on the strategy, leveraging the operational infrastructure, institutional knowledge, and networks that the firm has built over nearly two decades, an important element in cultivating future partnerships and driving value creating transactions. Furthermore, our Beyond Great learning community provides peer-to-peer networking for company leaders across the portfolio as well as tools and resources focused on shared elements of building successful and sustainable companies.

Transform

The true North Star at Third Rock remains the impact of its products on patients’ lives. Third Rock portfolio companies have now launched 27 products spanning oncology, cardiovascular disease, mental health and other areas of high unmet need. It is this that makes us most proud, as it means we are delivering on our mission of creating great companies that discover and develop products that make a difference for the patients we serve.